andrew schneider investigates

June 6, 2009

Silver nanoparticles may be a new life saver.

Filed under: Uncategorized — Andrew Schneider @ 06:51
Prof. Dash

Prof. Dash

Physicians have figured out that nanoparticles of silver may be a new way to prevent blood clots and some coronary artery disease, heart attack and stroke.

Dr. Debabrata Dash and colleagues at India’s Institute of Medical Sciences at Banaras Hindu University said they pursued the anti-clotting study because “patients urgently need new anti-thrombotic agents because traditionally prescribed medications too-often cause dangerous bleeding.”

The scientists found that when low levels of silver nano particles – only 1/50,000th the diameter of a human hair – were injected into the bloodstream laboratory mice, it reduced the ability of platelets to clump together by as much as 40 percent.

I asked a couple of cardiologists in Seattle and Boston about the reduction, and both said, if reproducible in humans, it could be a very big deal.

“Nanosilver appears to possess dual significant properties critically helpful to the health of mankind — antibacterial and antiplatelet — which together can have unique utilities, for example in coronary stents,” 
Dash said.

In email, Dash said that while the results are important, more work needs to be done.

When asked if he and his team were worried about harmful side effects from the injection of the silver particles.

“ Yes, the concerns remain as we have not carried out any human toxicity studies,” Dash told me but added that in the mice testing  In mouse model the nanoparticles “appeared to be quite safe. . . “

“However, like any other drug,” the doctor said, “one has to weigh between the benefits and side effects of nano silver before considering a therapeutic use.”

Dash’s study will be published later this month in the American Chemical Society’s peer-reviewed scientific journal Nano.

Here’s a link if you want to see the study.


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